New approaches for assessing genealogical relationships between bacteria
IDReC researchers led by Ji Zhang have recently published a paper entitled “Genome-by-genome approach for fast bacterial genealogical relationship evaluation” in the journal Bioinformatics. Recent advances in DNA sequencing technology have led to an increase in the amount of data available and the need for improved analysis tools.
The paper presents a new algorithm (Fast-GeP), which infers high-resolution genealogical relationships between bacterial isolates using whole-genome sequencing data. Fast-GeP has several advantages compared to conventional gene-by-gene approaches and will allow researchers to better understand the biological information in DNA sequence data.
Access to the full article is found at https://www.ncbi.nlm.nih.gov/pubmed/29608746